Iron Oxide/ Gold Core Shell Nano Particles (Fe3O4/Au, 99.9%, APS: 80-100nm, Metal Oxide Core)

Iron Oxide/ Gold Core-Shell Nano-Particles

Introduction

Iron oxide/gold core shell nanoparticles are composite nanomaterials that consist of a magnetic iron oxide core (usually magnetite, Fe₃O₄) coated with a thin layer of gold (Au). This core-shell architecture combines the superparamagnetic properties of the iron oxide core with the chemical stability, biocompatibility, and surface plasmon resonance (SPR) properties of the gold shell.

Sensing and Diagnostic Imaging

Surface Plasmon Resonance (SPR) Sensing: Iron oxide/gold core-shell nanoparticles The gold shell of can be used in SPR sensing applications. SPR occurs when free electrons in the gold shell resonate with incident light, which can be detected as a shift in the SPR signal. This makes Fe₃O₄/Au nanoparticles ideal for biosensing applications, where small changes in the local environment of the nanoparticle surface can be detected with high sensitivity.

Immunoassays and Diagnostics: Fe₃O₄/Au nanoparticles can be used in immunoassays for disease detection and biomarker analysis. The gold shell enhances the optical properties of the nanoparticles, making them ideal for colorimetric assays, while the iron oxide core can assist in the magnetic isolation of target analytes.

Therapeutic Applications

Magnetic Hyperthermia: The iron oxide core of Fe₃O₄/Au nanoparticles is capable of generating heat when exposed to an alternating magnetic field, which can be harnessed for magnetic hyperthermia treatments. This method involves using localized heat to destroy cancer cells or other abnormal tissues, providing a minimally invasive therapy for cancer.

Photothermal Therapy: Iron oxide/gold core-shell nanoparticles the enhances the photothermal effect by absorbing light in the near-infrared (NIR) range. This makes Fe₃O₄/Au nanoparticles ideal for photothermal cancer therapy, where the nanoparticles are targeted to tumor cells, and the gold shell absorbs NIR light, causing localized heating and tumor cell destruction.