Gelatin Nanoparticles (Purity: 99%, APS: <60nm)

Gelatin Nanoparticles

Gelatin nanoparticles (NPs) have been widely used as drug and gene carrier to targeted sick tissues including cancer, tuberculosis, HIV infection along with the treatment of vasospasm and restenosis, due to its biocompatibility and biodegradability. For instance, coating with gelatin lowers the cytotoxicity of quantum dots. Moreover, gelatin NPs have the ability to cross the blood-brain barrier, hence proven as a promising candidate to target brain disorders. Macrophage targeting with gelatin NPs for remedy of different diseases is repeatedly reported in previous years. In tissue engineering gelatin is actively utilized for construction of biological and life-long 3D scaffolds for bio-artificial tissues and organ production. Gelatins have a wide range of potential applications which needs to be unraveled in more detail. This review is mainly focused on the applications of gelatin NPs in biomedical sciences.

Nano-materials have been actively used in different applications like cancer therapy, drug delivery systems, tissue scaffolds, tissue engineering devices, diagnostics, and therapeutics in medicine. Strong association exists between drug and its carrier system, thereby allowing modulation of the pharmacokinetic properties and bio-distribution of the drugs. NPs are the most investigated system amongst different drug carriers and drug delivery systems. Controlled and targeted drug delivery are readily used in trails to enhance localization of drugs to specific tissues and cells, decreasing their interaction and potential toxicity thus increasing the therapeutic index of the existing drug.